The series focuses on the life of Concrete, formerly Ron Lithgow, whose brain was involuntarily transplanted by aliens into a hulking artificial body which is made up of a substance that closely resembles concrete.
As part of the back-story, he eventually escaped and made contact with the US Senator he worked for as a speechwriter. After a prolonged period of scientific tests and examinations, he was allowed to live on his own with the cover story that he was a cyborg constructed by the government.
In his new body, Concrete decides to use his tremendous strength, endurance and vision for a series of adventures he never thought of in his previous sedate life. Hiring a personal assistant writer and taking a female scientist who is assigned to monitor his body, Concrete has a wide variety of adventures.